{"id":2843,"date":"2017-05-15T20:23:47","date_gmt":"2017-05-16T00:23:47","guid":{"rendered":"http:\/\/www.thiscontemplativelife.com\/?p=2843"},"modified":"2017-05-15T20:23:47","modified_gmt":"2017-05-16T00:23:47","slug":"combined-role-of-vitamin-d-status-and-cyp24a1-in-the-transition-to-systemic-lupus-erythematosus-pubmed-ncbi","status":"publish","type":"post","link":"https:\/\/thiscontemplativelife.com\/index.php\/2017\/05\/15\/combined-role-of-vitamin-d-status-and-cyp24a1-in-the-transition-to-systemic-lupus-erythematosus-pubmed-ncbi\/","title":{"rendered":"Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. &#8211; PubMed &#8211; NCBI"},"content":{"rendered":"<p>Source: <em><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27283331?utm_content=bufferec30c&#038;utm_medium=social&#038;utm_source=facebook.com&#038;utm_campaign=buffer\">Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. &#8211; PubMed &#8211; NCBI<\/a><\/em><\/p>\n<p>From Dr Donald Thomas:<br \/>\nDo you know someone who is ANA positive and does not have lupus? Do you know family members of people who have lupus? They should consider having their vitamin D level checked and taking life long vitamin D supplements if they are deficient.<br \/>\nThese researchers showed that people who have a particular gene called CYP24A1 allele (esp if they have two of them) are at much higher risk for developing lupus when they are vitamin D deficient. Concentrate on the middle graph in the picture. Those who had 2 alleles (which increases the risk for lupus) were almost 5 times more likely to develop lupus when they were vitamin D deficient!<br \/>\nVitamin D is essential for the immune system to work properly. Studies show that simply being low in vitamin D causes immune abnormalities that we see in lupus.<br \/>\nIn my practice, I aim for a vitamin D level of around 40 ng\/mL based upon a study at Johns Hopkins that showed this to be an optimal goal to decrease lupus disease activity.<br \/>\nTAKE YOUR VITAMIN D!<br \/>\nSHARE with everyone who has lupus and everyone who is at increased risk.<br \/>\nby Donald Thomas, MD<br \/>\nhttp:\/\/buff.ly\/2rfQBY3<br \/>\nlupusencyclopedia@gmail.com<br \/>\nlupusencyclopedia.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus. &#8211; PubMed &#8211; NCBI From Dr Donald Thomas: Do&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[8],"tags":[],"_links":{"self":[{"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/posts\/2843"}],"collection":[{"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/comments?post=2843"}],"version-history":[{"count":0,"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/posts\/2843\/revisions"}],"wp:attachment":[{"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/media?parent=2843"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/categories?post=2843"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/thiscontemplativelife.com\/index.php\/wp-json\/wp\/v2\/tags?post=2843"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}