{"id":3031,"date":"2018-03-31T22:46:53","date_gmt":"2018-04-01T02:46:53","guid":{"rendered":"http:\/\/www.thiscontemplativelife.com\/?p=3031"},"modified":"2018-03-31T22:46:53","modified_gmt":"2018-04-01T02:46:53","slug":"mthfr-and-resistant-depression","status":"publish","type":"post","link":"https:\/\/thiscontemplativelife.com\/index.php\/2018\/03\/31\/mthfr-and-resistant-depression\/","title":{"rendered":"MTHFR and resistant depression"},"content":{"rendered":"
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Chris Masterjohn PhD:<\/div>\n
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Evolutionary Psychiatrist Emily Deans recently tweeted that she tests resistant depression patients for MTHFR status and finds ~50% of them to be C677T homozygous, which is the most severe reduction in MTHFR activity among the common polymorphisms. This is only in about 13% of the population.<\/p>\n

Although this is from an unpublished case series in a single clinical practice and not a peer-reviewed study of a random sample of a specific clinical population, it is still quite a staggering difference, close to 3.8 fold.<\/span><\/p>\n

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I believe anyone with mental health issues should be tested for methylation status.<\/p>\n<\/div>\n<\/div>\n

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\u00a0<\/span><\/span>@evolutionarypsy<\/b><\/span><\/a><\/p>\n
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