“Importantly, our data argue that the recognized increase in celiac disease prevalence in the general population over the last 50 years could be driven, at least in part, by perturbations in intestinal microbial ecology.”
http://bit.ly/1MzIBYq
Investigators interested in celiac disease have wondered why only 2 to 5 percent of genetically susceptible individuals develop the disease. Attention has focused on whether environmental determinants, including gut microorganisms, contribute to the development of celiac disease. Using a humanized mouse model of gluten sensitivity, a new study in the American Journal of Pathology found that the gut microbiome can play an important role in the body’s response to gluten.
